Dr. Charles Alessi is a globally recognised leader in preventative health, clinical policy, and population health management, with over 35 years of experience across the UK and international healthcare systems. As Chief Clinical Officer at Nightingale Health UK, he is at the forefront of advancing data-driven approaches to longevity and disease prevention.

Throughout his distinguished career, Dr. Alessi has held senior leadership roles including Global Chief Clinical Officer at HIMSS, Senior Advisor to Public Health England, and contributor to World Health Organization expert panels on neurosciences and dementia risk. He currently advises leading public health organisations such as IANPHI and Saudi Arabia’s Weqaya, and holds academic appointments in both the UK and Canada. His work spans clinical innovation, digital health transformation, and public health strategy, with extensive publications in the fields of population health and cognitive decline.

At the Longevity Med Summit, Dr. Alessi will present a forward-looking perspective on the evolving science of longevity, highlighting how new methodologies such as Nightingale Health’s clinically validated remote metabolic assessment are transforming how we measure, predict, and manage long-term health. By shifting from reactive diagnostics to predictive, iterative health insights, this new paradigm enables individuals and healthcare systems to track the impact of interventions in real time and make more informed decisions about longevity and wellbeing.

Topic of his presentation at the Longevity Med Summit 2026:

A new paradigm transforming longevity treatment – knowing what works 
The concept of managing health and wellness to promote longevity is now becoming a reality. As our understanding of the risk factors that affect health and longevity improves, the aspirations that James Fries first enunciated in the 1980s are becoming more attainable with a myriad of new interventions, therapeutic approaches now becoming more available. What however has been missing is a reliable, replicable and cost-effective methodology to enable a scientifically-based assessment of progress. This has now changed with the emergence of the Nightingale Health assessment.

This assessment is fundamentally different in that it projects clinical risk forward rather than reflecting the present, which is what most tests do. It is also iterative in that it changes as your behaviour affecting your risk factors change.
Thus, one can initiate a change and see this reflected in the Nightingale Health assessment.
Nightingale Health has introduced a remote health assessment, the world’s most clinically validated remote metabolic test, backed by 900+ publications.
Healthcare is changing very quickly. We can now assess impacts of change scientifically and accurately.  The impact of this on people and systems is going to be significant.